In the picturesque town of Weilburg, Germany, where history meets innovation, a remarkable event recently unfolded. Scientists, researchers, and experts from around the world gathered for the annual meeting of the DFG funded research program SPP2127, titled "Gene and Cell-Based Therapies to Counteract Neuroretinal Degeneration." This captivating event, hosted at the Castle Hotel Weilburg, was a melting pot of knowledge, ideas, and collaborations that promises to revolutionize the field of neuroretinal research. SPP2127: Pioneering the Fight Against Neuroretinal Degeneration Neuroretinal degeneration, a group of debilitating eye diseases that cause progressive vision loss, has long been a formidable challenge in the field of ophthalmology. However, thanks to the DFG (Deutsche Forschungsgemeinschaft) funded research program SPP2127, scientists have been granted the resources and platform to pool their talents and tackle this issue head-on. SPP2127 focuses on exploring gene and cell-based therapies to combat neuroretinal degeneration. These innovative approaches hold the promise of not just slowing down the progression of these diseases but potentially reversing the damage, restoring sight to those who have lost it. The Annual Meeting at Castle Hotel Weilburg: A Nexus of Scientific Brilliance The Castle Hotel Weilburg, with its rich history and stunning architecture, provided the perfect backdrop for this momentous scientific gathering. The event unfolded over three days, and each day was filled with intensive discussions, presentations of cutting-edge research, and the sharing of groundbreaking results. The collaborative spirit was palpable as researchers from diverse backgrounds and institutions engaged in spirited debates, shared insights, and brainstormed solutions to the complex challenges posed by neuroretinal degeneration. One of the highlights of the event was the announcement of start-up funding awards for young scientists. These awards not only recognize the potential of these emerging researchers but also invest in the future of neuroretinal research . Congratulations to all the recipients! Exploring Weilburg: A Glimpse into the Past While the primary focus of the meeting was on advancing science, the organizers also ensured that attendees had a chance to explore the charming old town of Weilburg. The second day included a city tour that allowed participants to immerse themselves in the rich history and culture of this beautiful German town. International Collaboration at Its Best SPP2127's annual meeting was not just a local event. It drew invited guests from renowned institutions in Ghent, Basel, Marburg, and the United States, including the National Institutes of Health (NIH). This international presence further enriched the discussions and emphasized the global significance of the research being conducted. Over the three days, the meeting provided a rare opportunity for most members of the consortium and numerous young scientists to come together, connect, and intensify their collaborations. The exchange of ideas, methodologies, and experiences was invaluable, fostering a sense of unity and purpose among all participants. A Bright Future for Neuroretinal Research The annual meeting of SPP2127 at Castle Hotel Weilburg was a testament to the power of collaborative research. As we move forward in the fight against neuroretinal degeneration, the connections made and knowledge shared during this event will undoubtedly pave the way for groundbreaking therapies and, ultimately, the restoration of vision for those in need. The Castle Hotel Weilburg may have witnessed centuries of history, but the SPP2127 meeting showcased the bright future of neuroretinal research, one where science and collaboration shine as beacons of hope for those affected by these debilitating diseases. As we eagerly await the developments that will emerge from this meeting, we can be certain that the quest to conquer neuroretinal degeneration is stronger and more unified than ever before.
The city of Dresden, known for its rich cultural heritage and scientific achievements, became a hub of innovation and knowledge during the recent Summer School organized by the Special Priority Programme (SPP2127). This three-day event brought together passionate young scientists, including PhD students and postdocs, to learn, collaborate, and unlock their potential in the field of research. Hosted at the renowned labs of esteemed researchers, Mike O. Karl and Marius Ader, the Summer School provided a unique platform for budding researchers to enhance their grant writing skills, gain valuable insights from fellow students' projects, and embark on their journey to secure internal grants within the SPP2127 framework. Fostering Future Leaders in Research The SPP2127 Summer School is part of the program's commitment to fostering the next generation of scientific leaders. This initiative was designed to empower young scientists by equipping them with essential skills, enabling them to contribute to the growing body of knowledge in their respective fields. The program focused on three key aspects: grant writing, project presentations, and the formulation of proposals for SPP2127 internal grants. Mastering the Art of Grant Writing The Summer School commenced with a series of workshops led by experts in grant writing, where participants gained insights into the nuances of crafting compelling proposals. Seasoned researchers shared their experiences, offering valuable advice on how to identify funding opportunities, structure proposals, and effectively communicate the significance of their research. The young scientists were encouraged to think innovatively, ensuring their projects aligned with the broader goals of SPP2127. Peer Learning and Project Presentations The summer school provided an excellent opportunity for attendees to showcase their ongoing research projects. Each participant presented their work to their peers, fostering an environment of collaboration and constructive feedback. This platform enabled budding scientists to refine their presentation skills and learn from diverse research approaches. The supportive atmosphere encouraged open discussions and stimulated fresh ideas, inspiring participants to tackle research challenges with renewed enthusiasm. The Path to SPP2127 Internal Grants The highlight of the Summer School was the final day, dedicated to present the proposals for SPP2127 internal grants. Armed with the knowledge acquired from grant writing workshops and inspired by peer interactions, the participants pitched their project proposals. Mentors Mike O. Karl and Marius Ader were on hand to provide personalized guidance and expertise. The young scientists were encouraged to explore interdisciplinary collaborations, aligning their projects with the overarching themes of SPP2127. Impact and Beyond The impact of the SPP2127 Summer School extended beyond the three-day event. The participants returned to their home institutions with newfound skills, confidence, and a broader network of collaborators. As they pursued their research projects, they remained connected through an online platform, facilitating continuous support and knowledge exchange. For many, the Summer School marked the beginning of an exciting journey towards securing internal grants within the SPP2127 program. The scientific community eagerly awaits the outcomes of these proposals, anticipating groundbreaking research that will shape the future of various fields.
T he official confirmation and refusal letters of the DFG were sent out to the applications for the second funding period some weeks ago. We are looking forward to a fresh mix of researchers and topics and can't wait to meet all the new and old PIs for our in-person kick off meeting in June! Still - we are sad that so many great researchers are not a part of the SPP anymore as they did not receive further funding. But we will continue to cooperate and foster our established networks from the first funding period! Until now, the consortium of the second funding period of the SPP 2127 met for a short online meeting to answer the most urgent questions and get to know each other a bit.
From the homepage of VIS: The field of regenerative medicine holds the promise of engineering damaged or diseased tissues previously thought to be irreparable. Some approaches involve the use of stem cells, progenitor cells, and novel materials. The NEI Office of Regenerative Medicine (ORM) has launched a new webinar series, called the Vision Innovation Seminars, to promote and disseminate cutting-edge research that is relevant to the vision community. Authors of recently published articles will present their work to the research community through this monthly webinar series. This seminar series is recorded and can be made available upon request. June 15, 2021 1:00-2:00 pm ET Mr. Giovanni Pasquini & Ms. Virginia Cora : Talk title TBD Recent Publication: Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in Vivo Genome Editing Mr. Giovanni Pasquini is a PhD student in the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB). His thesis work is focused on inferring and modulating Double Strand Break pathways activity by the study of transcriptomic data to guide in vivo Genome Editing approaches. His doctoral research is conducted at the Center for Regenerative Therapies of Dresden under the supervision of Prof. Dr. Volker Busskamp. Ms. Virginia Cora is a doctoral student in the Eberhard Karls University of Tübingen. Since 2018, she is part of the team of the Institute for Neuroanatomy and Developmental Biology (INDB) under the supervision of Prof. Dr. Stefan Liebau. Ms. Cora's work is focused on unravelling the effects of a mutation located in the gene Crumbs Homolog 1 (CRB1) that is associated with the insurgence of Retinitis Pigmentosa. For her investigations she is utilizing induced pluripotent stem cells (iPSCs)-derived retinal organoids as a model system. Additional reading relevant to talk: Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in Vivo Genome Editing A Cleared View on Retinal Organoids Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform
With the first funding period of the SPP 2127 coming to an end in the next months, the call for the second funding period was published. As the first funding period, the second funding period will be three years long. To further improve the development of therapeutic applications in this striving field of science, the results of the first three-year funding period, new data from current trials and preclinical experimentations as well as the improved understanding of the pathology of IRD require continued work at high level. Find more information on the call and how to apply on the homepage of the DFG: https://www.dfg.de/foerderung/info_wissenschaft/2021/info_wissenschaft_21_30/index.html
